---
id: "b919"
language: "en"
library: "tools"
official_url: "https://github.com/jwohlwend/boltz"
profile_updated_on: "2026-10-22"
---

# Boltz

Predicts biomolecular complex structures and estimates binding affinity with Boltz-2, with code and weights for local inference.

- Company / organization: Boltz project
- Category: Model development
- Official website: [https://github.com/jwohlwend/boltz](https://github.com/jwohlwend/boltz)
- Profile updated: 2026-10-22


## Overview

Boltz models biomolecular interactions from YAML-described inputs, returning predicted structures and scores. Boltz-2 adds binder probability and affinity estimates with different intended uses. The official repository licenses both code and weights under MIT. Inference requires a configured computing environment; optional public MSA services involve network requests. Predictions remain research outputs, not experimental measurements or clinical conclusions.

## Official sources and references

- [Official website](https://github.com/jwohlwend/boltz)
- [Documentation](https://github.com/jwohlwend/boltz/blob/main/README.md)

## Reading & subscriptions

- [Interactive profile](../../../products/boltz--b919.html)
- [Read](../../../read/en/products/boltz--b919.html)
- [JSON](../../../read/en/products/boltz--b919.json)

Descriptions summarize public information; consult official websites for features, pricing and regional availability.